The cell envelope subtilisin-like proteinase is a virulence determinant for Streptococcus suis
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چکیده
منابع مشابه
Subtilisin-like protease-1 secreted through type IV secretion system contributes to high virulence of Streptococcus suis 2
Streptococcus suis serotype 2 is an emerging zoonotic pathogen that triggered two outbreaks of streptococcal toxic shock syndrome (STSS) in China. Our previous research demonstrated that a type IV secretion system (T4SS) harbored in the 89K pathogenicity island contributes to the pathogenicity of S. suis 2. In the present study, a shotgun proteomics approach was employed to identify the effecto...
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Streptococcus suis serotype 2 is a porcine and human pathogen with adhesive and invasive properties. In other streptococci, large surface-associated proteins (>100 kDa) of the MSCRAMM family (microbial surface components recognizing adhesive matrix molecules) are key players in interactions with host tissue. In this study, we identified a novel opacity factor of S. suis (OFS) with structural ho...
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The contribution of iron transporter systems encoded by feo genes to the pathogenic traits of streptococci is largely unknown, despite the fact that those systems are required for the full virulence of several gram-negative bacterial species. In this work, we show that the swine pathogen and zoonotic agent Streptococcus suis has a feoAB operon similar to that encoding an iron transporter system...
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In a paper recently published (11), Rasmussen et al. have reported an interesting association between ribotype profiles of Streptococcus suis serotype 2 strains and clinical pathological observations of pigs from which the strains had been isolated. Their study provides further useful information on the use of molecular tools for epidemiological investigations. However, in their study, the auth...
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In recent months Hong Kong citizens have learned much about a lethal bacterium— Streptococcus suis— which has caused at least 38 deaths among 204 people infected in Sichuan province alone. They were told that this bacterium is widely spread among pigs; many carry it without developing any illness. Environmental factors such as high temperature or humidity might trigger off a clinical infection ...
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ژورنال
عنوان ژورنال: BMC Microbiology
سال: 2010
ISSN: 1471-2180
DOI: 10.1186/1471-2180-10-42